Complex Characterization of Germline Large Genomic Rearrangements of the BRCA1 and BRCA2 Genes in High-Risk Breast Cancer Patients—Novel Variants from a Large National Center

Large genomic rearrangements (LGRs) affecting one or more exons of BRCA1 and BRCA2 constitute a significant part of the mutation spectrum of these genes. Since 2004, the National Institute of Oncology, Hungary, has been involved in screening for LGRs of breast or ovarian cancer families enrolled for...

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Detalles Bibliográficos
Autores principales: Bozsik, Anikó, Pócza, Tímea, Papp, János, Vaszkó, Tibor, Butz, Henriett, Patócs, Attila, Oláh, Edit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370166/
https://www.ncbi.nlm.nih.gov/pubmed/32629901
http://dx.doi.org/10.3390/ijms21134650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370166/
https://www.ncbi.nlm.nih.gov/pubmed/32629901
http://dx.doi.org/10.3390/ijms21134650

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