Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis

Neutrophils are involved in the alveolitis of idiopathic pulmonary fibrosis (IPF). However, their pathogenic mechanisms are still poorly understood. Nintedanib has antifibrotic and anti-inflammatory activity in IPF. This study aimed to investigate the regulatory mechanism of nintedanib on neutrophil...

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Detalles Bibliográficos
Autores principales: Chen, Wei-Chih, Chen, Nien-Jung, Chen, Hsin-Pai, Yu, Wen-Kuang, Su, Vincent Yi-Fong, Chen, Hao, Wu, Huai-Hsuan, Yang, Kuang-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370174/
https://www.ncbi.nlm.nih.gov/pubmed/32630825
http://dx.doi.org/10.3390/ijms21134735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370174/
https://www.ncbi.nlm.nih.gov/pubmed/32630825
http://dx.doi.org/10.3390/ijms21134735

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