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Deletion of NRXN1α impairs long-range and local connectivity in amygdala fear circuit

Neurexins are a family of presynaptic cell adhesion proteins that regulate synaptic structure and maintain normal synaptic transmission. Mutations in the α-isoform of neurexin1-gene (NRXN1α) are linked with cognitive and emotional dysregulation, which are heavily dependent on the amygdala and medial...

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Detalles Bibliográficos
Autores principales: Asede, Douglas, Joseph, Asnel, Bolton, McLean M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370229/
https://www.ncbi.nlm.nih.gov/pubmed/32684634
http://dx.doi.org/10.1038/s41398-020-00926-y