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Aldosterone Induces DNA Damage and Activation of Nrf2 Mainly in Tubuli of Mouse Kidneys

Hypertensive patients have an increased risk of developing chronic kidney disease (CKD). Many of these patients have increased levels of the blood pressure regulating mineralocorticoid aldosterone. As a protection against aldosterone-induced damage, kidney cells can upregulate key regulators of the...

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Detalles Bibliográficos
Autores principales: Balhorn, Ronja, Hartmann, Christina, Schupp, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370281/
https://www.ncbi.nlm.nih.gov/pubmed/32630085
http://dx.doi.org/10.3390/ijms21134679