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Mannose-binding lectin has a direct deleterious effect on ischemic brain microvascular endothelial cells

Mannose-binding lectin (MBL), an initiator of the lectin pathway, is detrimental in ischemic stroke. MBL deposition on the ischemic endothelium indicates the beginning of its actions, but downstream mechanisms are not clear yet. We investigated MBL interactions with the ischemic endothelium by expos...

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Detalles Bibliográficos
Autores principales: Neglia, Laura, Fumagalli, Stefano, Orsini, Franca, Zanetti, Adriana, Perego, Carlo, De Simoni, Maria-Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370363/
https://www.ncbi.nlm.nih.gov/pubmed/31495300
http://dx.doi.org/10.1177/0271678X19874509