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Enhancer prediction in the human genome by probabilistic modelling of the chromatin feature patterns

BACKGROUND: The binding sites of transcription factors (TFs) and the localisation of histone modifications in the human genome can be quantified by the chromatin immunoprecipitation assay coupled with next-generation sequencing (ChIP-seq). The resulting chromatin feature data has been successfully a...

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Detalles Bibliográficos
Autores principales: Osmala, Maria, Lähdesmäki, Harri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370432/
https://www.ncbi.nlm.nih.gov/pubmed/32689977
http://dx.doi.org/10.1186/s12859-020-03621-3