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SUV39H1-DNMT3A-mediated epigenetic regulation of Tim-3 and galectin-9 in the cervical cancer

BACKGROUND: Methylation of histone 3 at lysine 9 (H3K9) and DNA methylation are epigenetic marks correlated with genes silencing. The tumor microenvironment significantly influences therapeutic responses and clinical outcomes. The epigenetic-regulation mechanism of the costimulatory factors Tim-3 an...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Tian, Sijuan, Zhao, Minyi, Yang, Ting, Quan, Shimin, Yang, Qing, Song, Lihua, Yang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370487/
https://www.ncbi.nlm.nih.gov/pubmed/32699524
http://dx.doi.org/10.1186/s12935-020-01380-y