Cargando…

SUV39H1-DNMT3A-mediated epigenetic regulation of Tim-3 and galectin-9 in the cervical cancer

BACKGROUND: Methylation of histone 3 at lysine 9 (H3K9) and DNA methylation are epigenetic marks correlated with genes silencing. The tumor microenvironment significantly influences therapeutic responses and clinical outcomes. The epigenetic-regulation mechanism of the costimulatory factors Tim-3 an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Li, Tian, Sijuan, Zhao, Minyi, Yang, Ting, Quan, Shimin, Yang, Qing, Song, Lihua, Yang, Xiaofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370487/ https://www.ncbi.nlm.nih.gov/pubmed/32699524 http://dx.doi.org/10.1186/s12935-020-01380-y

Ejemplares similares

Crosstalk between histone modification and DNA methylation orchestrates the epigenetic regulation of the costimulatory factors, Tim-3 and galectin-9, in cervical cancer
por: Zhang, Li, et al.
Publicado: (2019)

Histone methyltransferase SUV39H2 regulates cell growth and chemosensitivity in glioma via regulation of hedgehog signaling
por: Wang, Ran, et al.
Publicado: (2019)

Whole exome sequencing highlights rare variants in CTCF, DNMT1, DNMT3A, EZH2 and SUV39H1 as associated with FSHD
por: Strafella, Claudia, et al.
Publicado: (2023)

Histone methyltransferase SUV39H2 regulates LSD1-dependent CDH1 expression and promotes epithelial mesenchymal transition of osteosarcoma
por: Miao, Yingying, et al.
Publicado: (2021)

Tim3 binding to galectin-9 stimulates antimicrobial immunity
por: Jayaraman, Pushpa, et al.
Publicado: (2010)

TIM-3 Does Not Act as a Receptor for Galectin-9
por: Leitner, Judith, et al.
Publicado: (2013)

The histone methyltransferase Suv39h regulates 3T3-L1 adipogenesis
por: Jing, Jia, et al.
Publicado: (2020)

H3K9 Methyltransferases Suv39h1 and Suv39h2 Control the Differentiation of Neural Progenitor Cells in the Adult Hippocampus
por: Guerra, Miguel V., et al.
Publicado: (2022)

DNMT1 facilitates growth of breast cancer by inducing MEG3 hyper-methylation
por: Zhu, Xiaotao, et al.
Publicado: (2022)

Structure, Activity and Function of the Suv39h1 and Suv39h2 Protein Lysine Methyltransferases
por: Weirich, Sara, et al.
Publicado: (2021)

Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions
por: Mauger, Oriane, et al.
Publicado: (2015)

Histone Methyltransferases SUV39H1 and G9a and DNA Methyltransferase DNMT1 in Penumbra Neurons and Astrocytes after Photothrombotic Stroke
por: Sharifulina, Svetlana, et al.
Publicado: (2021)

Automethylation-induced conformational switch in Clr4/Suv39h maintains epigenetic stability
por: Iglesias, Nahid, et al.
Publicado: (2018)

The immune receptor Tim-3 acts as a trafficker in a Tim-3/galectin-9 autocrine loop in human myeloid leukemia cells
por: Gonçalves Silva, Isabel, et al.
Publicado: (2016)

DNMT3A mutations and clinical features in Chinese patients with acute myeloid leukemia
por: Lu, Quanyi, et al.
Publicado: (2013)

The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer
por: Yasinska, Inna M., et al.
Publicado: (2019)

The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction
por: Yang, Guang, et al.
Publicado: (2017)

Upregulation of the Tim-3/Galectin-9 Pathway of T Cell Exhaustion in Chronic Hepatitis B Virus Infection
por: Nebbia, Gaia, et al.
Publicado: (2012)

SUV39H2 epigenetic silencing controls fate conversion of epidermal stem and progenitor cells
por: Balmer, Pierre, et al.
Publicado: (2021)

The Oncogenic Potential of SUV39H2: A Comprehensive and Perspective View
por: Li, Baihui, et al.
Publicado: (2019)

Involvement of Galectin-9/TIM-3 Pathway in the Systemic Inflammatory Response in Early-Onset Preeclampsia
por: Miko, Eva, et al.
Publicado: (2013)

Decreased Galectin-9 and Increased Tim-3 Expression Are Related to Poor Prognosis in Gastric Cancer
por: Jiang, Jing, et al.
Publicado: (2013)

Down-regulation of DNMT3b in PC3 cells effects locus-specific DNA methylation, and represses cellular growth and migration
por: Yaqinuddin, Ahmed, et al.
Publicado: (2008)

Identification of SUV39H2 as a potential oncogene in lung adenocarcinoma
por: Zheng, Yu, et al.
Publicado: (2018)

CD8+T cell responsiveness to anti-PD-1 is epigenetically regulated by Suv39h1 in melanomas
por: Niborski, Leticia Laura, et al.
Publicado: (2022)

Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy
por: Yang, Riyao, et al.
Publicado: (2021)

Silencing long non-coding RNA HOTAIR exerts anti-oncogenic effect on human acute myeloid leukemia via demethylation of HOXA5 by inhibiting Dnmt3b
por: Wang, Si-Li, et al.
Publicado: (2019)

Targeting Suppressor of Variegation 3-9 Homologue 2 (SUV39H2) in Acute Lymphoblastic Leukemia (ALL)()
por: Mutonga, Martin, et al.
Publicado: (2015)

Negative immune factors might predominate local tumor immune status and promote carcinogenesis in cervical carcinoma
por: Zhao, Minyi, et al.
Publicado: (2017)

Metformin inhibits SUV39H1-mediated migration of prostate cancer cells
por: Yu, T, et al.
Publicado: (2017)

SUV39H1 regulates corneal epithelial wound healing via H3K9me3-mediated repression of p27
por: Yang, Shuai, et al.
Publicado: (2022)

Peripheral Blood TIM-3 Positive NK and CD8+ T Cells throughout Pregnancy: TIM-3/Galectin-9 Interaction and Its Possible Role during Pregnancy
por: Meggyes, Matyas, et al.
Publicado: (2014)

The immunologic advantage of recurrent nasopharyngeal carcinoma from the viewpoint of Galectin-9/Tim-3-related changes in the tumour microenvironment
por: Chen, Tseng-Cheng, et al.
Publicado: (2017)

Functional expression of Tim-3 on blasts and clinical impact of its ligand galectin-9 in myelodysplastic syndromes
por: Asayama, Toshio, et al.
Publicado: (2017)

Upregulated Tim-3/galectin-9 expressions in acute lung injury in a murine malarial model
por: Liu, Jinfeng, et al.
Publicado: (2015)

Tim-3 Is Upregulated in NK Cells during Early Pregnancy and Inhibits NK Cytotoxicity toward Trophoblast in Galectin-9 Dependent Pathway
por: Sun, Jintang, et al.
Publicado: (2016)

Overexpression of trefoil factor 3 (TFF3) contributes to the malignant progression in cervical cancer cells
por: Yuan, Zhaohu, et al.
Publicado: (2017)

RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin
por: Johnson, Whitney L, et al.
Publicado: (2017)

SUV39H1 Reduction Is Implicated in Abnormal Inflammation in COPD
por: Chen, Tzu-Tao, et al.
Publicado: (2017)

SUV39 SET domains mediate crosstalk of heterochromatic histone marks
por: Stirpe, Alessandro, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_v9ra837pevtlb9sep6o49atmce