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Prophylactic therapy with human amniotic fluid stem cells improved survival in a rat model of lipopolysaccharide-induced neonatal sepsis through immunomodulation via aggregates with peritoneal macrophages

BACKGROUND: Despite recent advances in neonatal care, sepsis remains a leading cause of mortality in neonates. Mesenchymal stem cells derived from various tissues, such as bone marrow, umbilical cord, and adipose tissue, have beneficial effects on adult sepsis. Although human amniotic fluid stem cel...

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Detalles Bibliográficos
Autores principales: Sato, Yu, Ochiai, Daigo, Abe, Yushi, Masuda, Hirotaka, Fukutake, Marie, Ikenoue, Satoru, Kasuga, Yoshifumi, Shimoda, Masayuki, Kanai, Yae, Tanaka, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370504/
https://www.ncbi.nlm.nih.gov/pubmed/32690106
http://dx.doi.org/10.1186/s13287-020-01809-1