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Prophylactic therapy with human amniotic fluid stem cells improved survival in a rat model of lipopolysaccharide-induced neonatal sepsis through immunomodulation via aggregates with peritoneal macrophages
BACKGROUND: Despite recent advances in neonatal care, sepsis remains a leading cause of mortality in neonates. Mesenchymal stem cells derived from various tissues, such as bone marrow, umbilical cord, and adipose tissue, have beneficial effects on adult sepsis. Although human amniotic fluid stem cel...
Autores principales: | Sato, Yu, Ochiai, Daigo, Abe, Yushi, Masuda, Hirotaka, Fukutake, Marie, Ikenoue, Satoru, Kasuga, Yoshifumi, Shimoda, Masayuki, Kanai, Yae, Tanaka, Mamoru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370504/ https://www.ncbi.nlm.nih.gov/pubmed/32690106 http://dx.doi.org/10.1186/s13287-020-01809-1 |
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