Cytokine-induced molecular responses in airway smooth muscle cells inform genome-wide association studies of asthma

BACKGROUND: A challenge in the post-GWAS era is to assign function to disease-associated variants. However, available resources do not include all tissues or environmental exposures that are relevant to all diseases. For example, exaggerated bronchoconstriction of airway smooth muscle cells (ASMCs)...

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Detalles Bibliográficos
Autores principales: Thompson, Emma E., Dang, Quynh, Mitchell-Handley, Blair, Rajendran, Kavitha, Ram-Mohan, Sumati, Solway, Julian, Ober, Carole, Krishnan, Ramaswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370514/
https://www.ncbi.nlm.nih.gov/pubmed/32690065
http://dx.doi.org/10.1186/s13073-020-00759-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370514/
https://www.ncbi.nlm.nih.gov/pubmed/32690065
http://dx.doi.org/10.1186/s13073-020-00759-w

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