Clonal evolution driven by superdriver mutations

BACKGROUND: Tumors are widely recognized to progress through clonal evolution by sequentially acquiring selectively advantageous genetic alterations that significantly contribute to tumorigenesis and thus are termned drivers. Some cancer drivers, such as TP53 point mutation or EGFR copy number gain,...

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Detalles Bibliográficos
Autores principales: Grossmann, Patrick, Cristea, Simona, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370525/
https://www.ncbi.nlm.nih.gov/pubmed/32689942
http://dx.doi.org/10.1186/s12862-020-01647-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370525/
https://www.ncbi.nlm.nih.gov/pubmed/32689942
http://dx.doi.org/10.1186/s12862-020-01647-y

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