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Intrathecal pemetrexed combined with involved-field radiotherapy as a first-line intra-CSF therapy for leptomeningeal metastases from solid tumors: a phase I/II study

PURPOSE: A phase I/II study of intrathecal pemetrexed (IP) combined with involved-field radiotherapy (IFRT) was performed to determine feasibility, safety, and antitumor activity for leptomeningeal metastases (LM) from solid tumors. METHODS: Participants first received induction IP administration, f...

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Detalles Bibliográficos
Autores principales: Pan, Zhenyu, Yang, Guozi, He, Hua, Cui, Jiuwei, Li, Wei, Yuan, Tingting, Chen, Kunzhi, Jiang, Tongchao, Gao, Pengxiang, Sun, Yanan, Cong, Xiaofeng, Li, Zhi, Wang, Yongxiang, Pang, Xiaochuan, Song, Yuanyuan, Zhao, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370561/
https://www.ncbi.nlm.nih.gov/pubmed/32733606
http://dx.doi.org/10.1177/1758835920937953