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Autophagy regulates the localization and degradation of p16(INK4a)

The tumor suppressor protein p16(INK4a) (p16) is a well‐established hallmark of aging that induces cellular senescence in response to stress. Previous studies have focused primarily on p16 regulation at the transcriptional level; comparatively little is known about the protein's intracellular l...

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Detalles Bibliográficos
Autores principales: Coryell, Philip R., Goraya, Supreet K., Griffin, Katherine A., Redick, Margaret A., Sisk, Samuel R., Purvis, Jeremy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370706/
https://www.ncbi.nlm.nih.gov/pubmed/32662244
http://dx.doi.org/10.1111/acel.13171