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Prominin‐1‐expressing hepatic progenitor cells induce fibrogenesis in murine cholestatic liver injury

Cholestatic liver injury is associated with intrahepatic biliary fibrosis, which can progress to cirrhosis. Resident hepatic progenitor cells (HPCs) expressing Prominin‐1 (Prom1 or CD133) become activated and participate in the expansion of cholangiocytes known as the ductular reaction. Previously,...

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Detalles Bibliográficos
Autores principales: Fenlon, Michael, Short, Celia, Xu, Jiabo, Malkoff, Nicolas, Mahdi, Elaa, Hough, Michelle, Glazier, Alison, Lee, Calvin, Asahina, Kinji, Wang, Kasper S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370750/
https://www.ncbi.nlm.nih.gov/pubmed/32686913
http://dx.doi.org/10.14814/phy2.14508