NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism

The survival and recurrence of dormant tumour cells following therapy is a leading cause of death in cancer patients. The metabolic properties of these cells are likely distinct from those of rapidly growing tumours. Here we show that Her2 down-regulation in breast cancer cells promotes changes in c...

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Detalles Bibliográficos
Autores principales: Fox, Douglas B., Garcia, Nina Marie G., McKinney, Brock J., Lupo, Ryan, Noteware, Laura C., Newcomb, Rachel, Liu, Juan, Locasale, Jason W., Hirschey, Matthew D., Alvarez, James V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370851/
https://www.ncbi.nlm.nih.gov/pubmed/32691018
http://dx.doi.org/10.1038/s42255-020-0191-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370851/
https://www.ncbi.nlm.nih.gov/pubmed/32691018
http://dx.doi.org/10.1038/s42255-020-0191-z

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