SARS-CoV-2 Entry Receptor ACE2 Is Expressed on Very Small CD45(−) Precursors of Hematopoietic and Endothelial Cells and in Response to Virus Spike Protein Activates the Nlrp3 Inflammasome

Angiotensin-converting enzyme 2 (ACE2) plays an important role as a member of the renin–angiotensin–aldosterone system (RAAS) in regulating the conversion of angiotensin II (Ang II) into angiotensin (1–7) (Ang [1–7]). But at the same time, while expressed on the surface of human cells, ACE2 is the e...

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Detalles Bibliográficos
Autores principales: Ratajczak, Mariusz Z., Bujko, Kamila, Ciechanowicz, Andrzej, Sielatycka, Kasia, Cymer, Monika, Marlicz, Wojciech, Kucia, Magda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370872/
https://www.ncbi.nlm.nih.gov/pubmed/32691370
http://dx.doi.org/10.1007/s12015-020-10010-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370872/
https://www.ncbi.nlm.nih.gov/pubmed/32691370
http://dx.doi.org/10.1007/s12015-020-10010-z

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