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Characterization of colibactin-associated mutational signature in an Asian oral squamous cell carcinoma and in other mucosal tumor types

Mutational signatures can reveal the history of mutagenic processes that cells were exposed to before and during tumorigenesis. We expect that as-yet-undiscovered mutational processes will shed further light on mutagenesis leading to carcinogenesis. With this in mind, we analyzed the mutational spec...

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Detalles Bibliográficos
Autores principales: Boot, Arnoud, Ng, Alvin W.T., Chong, Fui Teen, Ho, Szu-Chi, Yu, Willie, Tan, Daniel S.W., Iyer, N. Gopalakrishna, Rozen, Steven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370881/
https://www.ncbi.nlm.nih.gov/pubmed/32661091
http://dx.doi.org/10.1101/gr.255620.119