A long-read RNA-seq approach to identify novel transcripts of very large genes

RNA-seq is widely used for studying gene expression, but commonly used sequencing platforms produce short reads that only span up to two exon junctions per read. This makes it difficult to accurately determine the composition and phasing of exons within transcripts. Although long-read sequencing imp...

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Detalles Bibliográficos
Autores principales: Uapinyoying, Prech, Goecks, Jeremy, Knoblach, Susan M., Panchapakesan, Karuna, Bonnemann, Carsten G., Partridge, Terence A., Jaiswal, Jyoti K., Hoffman, Eric P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370890/
https://www.ncbi.nlm.nih.gov/pubmed/32660935
http://dx.doi.org/10.1101/gr.259903.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370890/
https://www.ncbi.nlm.nih.gov/pubmed/32660935
http://dx.doi.org/10.1101/gr.259903.119

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