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ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)–Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm

OBJECTIVE: ADAM (a disintegrin and metalloproteinase) 15—a membrane-bound metalloprotease from the ADAM (disintegrin and metalloproteinase) family—has been linked to endothelial permeability, inflammation, and metastasis. However, its function in aortic aneurysm has not been explored. We aimed to de...

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Detalles Bibliográficos
Autores principales: Jana, Sayantan, Chute, Michael, Hu, Mei, Winkelaar, Gerrit, Owen, Caroline A., Oudit, Gavin Y., Kassiri, Zamaneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370975/
https://www.ncbi.nlm.nih.gov/pubmed/32522006
http://dx.doi.org/10.1161/ATVBAHA.120.314600