PLD2–PI(4,5)P2 interactions in fluid phase membranes: Structural modeling and molecular dynamics simulations

Interaction of phospholipase D2 (PLD2) with phosphatidylinositol (4,5)-bisphosphate (PIP(2)) is regarded as the critical step of numerous physiological processes. Here we build a full-length model of human PLD2 (hPLD2) combining template-based and ab initio modeling techniques and use microsecond al...

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Detalles Bibliográficos
Autores principales: Han, Kyungreem, Pastor, Richard W., Fenollar–Ferrer, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371163/
https://www.ncbi.nlm.nih.gov/pubmed/32687545
http://dx.doi.org/10.1371/journal.pone.0236201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371163/
https://www.ncbi.nlm.nih.gov/pubmed/32687545
http://dx.doi.org/10.1371/journal.pone.0236201

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