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The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP

The membrane protein ANKH was known to prevent pathological mineralization of joints and was thought to export pyrophosphate (PPi) from cells. This did not explain, however, the presence of ANKH in tissues, such as brain, blood vessels and muscle. We now report that in cultured cells ANKH exports AT...

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Detalles Bibliográficos
Autores principales: Szeri, Flora, Lundkvist, Stefan, Donnelly, Sylvia, Engelke, Udo F. H., Rhee, Kyu, Williams, Charlene J., Sundberg, John P., Wevers, Ron A., Tomlinson, Ryan E., Jansen, Robert S., van de Wetering, Koen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371198/
https://www.ncbi.nlm.nih.gov/pubmed/32639996
http://dx.doi.org/10.1371/journal.pgen.1008884