Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation

Influenza A virus (IAV) binds its host cell using the major viral surface protein hemagglutinin (HA). HA recognizes sialic acid, a plasma membrane glycan that functions as the specific primary attachment factor (AF). Since sialic acid alone cannot fulfill a signaling function, the virus needs to act...

Descripción completa

Detalles Bibliográficos
Autores principales: Sieben, Christian, Sezgin, Erdinc, Eggeling, Christian, Manley, Suliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371231/
https://www.ncbi.nlm.nih.gov/pubmed/32639985
http://dx.doi.org/10.1371/journal.ppat.1008656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371231/
https://www.ncbi.nlm.nih.gov/pubmed/32639985
http://dx.doi.org/10.1371/journal.ppat.1008656

Ejemplares similares