In situ vaccination at a peripheral tumor site augments response against melanoma brain metastases

BACKGROUND: Immune checkpoint inhibition (ICI) alone is not efficacious for a large number of patients with melanoma brain metastases. We previously established an in situ vaccination (ISV) regimen combining radiation and immunocytokine to enhance response to ICIs. Here, we tested whether ISV inhibi...

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Detalles Bibliográficos
Autores principales: Clark, Paul A, Sriramaneni, Raghava N, Jin, Won Jong, Jagodinsky, Justin C, Bates, Amber M, Jaquish, Abigail A, Anderson, Bryce R, Le, Trang, Lubin, Jonathan A, Chakravarty, Ishan, Arthur, Ian S, Heinze, Clinton M, Guy, Emily I, Kler, Jasdeep, Klar, Kelsey A, Carlson, Peter M, Kim, Kyung Mann, Kuo, John S, Morris, Zachary S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371368/
https://www.ncbi.nlm.nih.gov/pubmed/32690669
http://dx.doi.org/10.1136/jitc-2020-000809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371368/
https://www.ncbi.nlm.nih.gov/pubmed/32690669
http://dx.doi.org/10.1136/jitc-2020-000809

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