Alu-Mediated MEN1 Gene Deletion and Loss of Heterozygosity in a Patient with Multiple Endocrine Neoplasia Type 1

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder caused by mutations of the tumor suppressor gene MEN1. Most of the germline MEN1 gene mutations have been small mutations, and the whole gene deletion is rarely observed. In the present study, we revealed Alu retrotransposo...

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Detalles Bibliográficos
Autores principales: Yoshiji, Satoshi, Iwasaki, Yorihiro, Iwasaki, Kanako, Honjo, Sachiko, Hirano, Koichi, Ono, Katsuhiko, Yamazaki, Yuto, Sasano, Hironobu, Hamasaki, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371388/
https://www.ncbi.nlm.nih.gov/pubmed/32715270
http://dx.doi.org/10.1210/jendso/bvaa051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371388/
https://www.ncbi.nlm.nih.gov/pubmed/32715270
http://dx.doi.org/10.1210/jendso/bvaa051

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