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Aromatic interactions with membrane modulate human BK channel activation

Large-conductance potassium (BK) channels are transmembrane (TM) proteins that can be synergistically and independently activated by membrane voltage and intracellular Ca(2+). The only covalent connection between the cytosolic Ca(2+) sensing domain and the TM pore and voltage sensing domains is a 15...

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Detalles Bibliográficos
Autores principales: Yazdani, Mahdieh, Zhang, Guohui, Jia, Zhiguang, Shi, Jingyi, Cui, Jianmin, Chen, Jianhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371421/
https://www.ncbi.nlm.nih.gov/pubmed/32597752
http://dx.doi.org/10.7554/eLife.55571