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MEIS-mediated suppression of human prostate cancer growth and metastasis through HOXB13-dependent regulation of proteoglycans

The molecular roles of HOX transcriptional activity in human prostate epithelial cells remain unclear, impeding the implementation of new treatment strategies for cancer prevention and therapy. MEIS proteins are transcription factors that bind and direct HOX protein activity. MEIS proteins are putat...

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Detalles Bibliográficos
Autores principales: VanOpstall, Calvin, Perike, Srikanth, Brechka, Hannah, Gillard, Marc, Lamperis, Sophia, Zhu, Baizhen, Brown, Ryan, Bhanvadia, Raj, Vander Griend, Donald J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371429/
https://www.ncbi.nlm.nih.gov/pubmed/32553107
http://dx.doi.org/10.7554/eLife.53600