The JNK pathway represents a novel target in the treatment of rheumatoid arthritis through the suppression of MMP-3

BACKGROUND AND AIM: The pathophysiology of rheumatoid arthritis (RA) is characterized by excess production of pro-inflammatory cytokines, including tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6) by neutrophils and macrophages in synovium. Additionally, these cytoki...

Descripción completa

Detalles Bibliográficos
Autores principales: Kanai, Tomotake, Kondo, Naoki, Okada, Masayasu, Sano, Hiroshige, Okumura, Go, Kijima, Yasufumi, Ogose, Akira, Kawashima, Hiroyuki, Endo, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371465/
https://www.ncbi.nlm.nih.gov/pubmed/32131874
http://dx.doi.org/10.1186/s13018-020-01595-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371465/
https://www.ncbi.nlm.nih.gov/pubmed/32131874
http://dx.doi.org/10.1186/s13018-020-01595-9

Ejemplares similares