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lncRNA GAS5 Is Upregulated in Osteoporosis and Downregulates miR-21 to Promote Apoptosis of Osteoclasts

BACKGROUND: It has been reported that lncRNA growth arrest-specific transcript 5 (GAS5) interacts with miR-21, which plays critical roles in osteoporosis. The involvement of GAS5 in osteoporosis was investigated in this study. METHODS: Expression levels of GAS5 and miR-21 in plasma of both osteoporo...

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Detalles Bibliográficos
Autores principales: Cong, Chunlei, Tian, Jun, Gao, Tianqi, Zhou, Changlin, Wang, Yuxiang, Cui, Xintao, Zhu, Liyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371557/
https://www.ncbi.nlm.nih.gov/pubmed/32764903
http://dx.doi.org/10.2147/CIA.S235197