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Chitosan hydrogel incorporated with dental pulp stem cell-derived exosomes alleviates periodontitis in mice via a macrophage-dependent mechanism

Periodontitis is caused by host immune-inflammatory response to bacterial insult. A high proportion of pro-inflammatory macrophages to anti-inflammatory macrophages leads to the pathogenesis of periodontitis. As stem cell-derived exosomes can modulate macrophage phenotype, dental pulp stem cell-deri...

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Detalles Bibliográficos
Autores principales: Shen, Zongshan, Kuang, Shuhong, Zhang, Yong, Yang, Mingmei, Qin, Wei, Shi, Xuetao, Lin, Zhengmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371600/
https://www.ncbi.nlm.nih.gov/pubmed/32743122
http://dx.doi.org/10.1016/j.bioactmat.2020.07.002