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MAF1 is a chronic repressor of RNA polymerase III transcription in the mouse
Maf1(−/−) mice are lean, obesity-resistant and metabolically inefficient. Their increased energy expenditure is thought to be driven by a futile RNA cycle that reprograms metabolism to meet an increased demand for nucleotides stemming from the deregulation of RNA polymerase (pol) III transcription....
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371695/ https://www.ncbi.nlm.nih.gov/pubmed/32686713 http://dx.doi.org/10.1038/s41598-020-68665-0 |