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Inhibition of mitotic kinase Mps1 promotes cell death in neuroblastoma

Neuroblastoma is the most common paediatric cancer type. Patients diagnosed with high-risk neuroblastoma have poor prognosis and occasionally tumours relapse. As a result, novel treatment strategies are needed for relapse and refractory neuroblastoma patients. Here, we found that high expression of...

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Detalles Bibliográficos
Autores principales: Simon Serrano, Sonia, Sime, Wondossen, Abassi, Yasmin, Daams, Renée, Massoumi, Ramin, Jemaà, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371706/
https://www.ncbi.nlm.nih.gov/pubmed/32686724
http://dx.doi.org/10.1038/s41598-020-68829-y