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1.2 MV/cm pulsed electric fields promote transthyretin aggregate degradation

Numerous theoretical studies have been conducted on the effects of high-voltage electric fields on proteins, but few have produced experimental evidence. To acquire experimental data for the amyloid disassemble theory, we exposed transthyretin aggregates to 1 ns 1.26 MV/cm pulsed electric fields (PE...

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Detalles Bibliográficos
Autores principales: Urabe, Gen, Sato, Takashi, Nakamura, Gomaru, Kobashigawa, Yoshihiro, Morioka, Hiroshi, Katsuki, Sunao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371718/
https://www.ncbi.nlm.nih.gov/pubmed/32686729
http://dx.doi.org/10.1038/s41598-020-68681-0