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A Small-Scale Medication of Leflunomide as a Treatment of COVID-19 in an Open-Label Blank-Controlled Clinical Trial

We recently reported that inhibitors against human dihydroorotate dehydrogenase (DHODH) have broad-spectrum antiviral activities including their inhibitory efficacies on SARS-CoV-2 replication in infected cells. However, there are limited data from clinical studies to prove the application of DHODH...

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Detalles Bibliográficos
Autores principales: Hu, Ke, Wang, Mengmei, Zhao, Yang, Zhang, Yunting, Wang, Tao, Zheng, Zhishui, Li, Xiaochen, Zeng, Shaolin, Zhao, Dong, Li, Honglin, Xu, Ke, Lan, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371831/
https://www.ncbi.nlm.nih.gov/pubmed/32696396
http://dx.doi.org/10.1007/s12250-020-00258-7