Inactivating p53 is essential for nerve growth factor receptor to promote melanoma-initiating cell-stemmed tumorigenesis

Nerve growth factor receptor (NGFR, CD271, or p75NTR) is highly expressed in melanoma-initiating cells (MICs) and is critical for their proliferation and tumorigenesis, and yet the underlying mechanism(s) remain incompletely understood. We previously showed that NGFR inhibits p53 activity in a negat...

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Detalles Bibliográficos
Autores principales: Jiang, Leiwei, Huang, Shibo, Wang, Jieqiong, Zhang, Yiwei, Xiong, Yuqing, Zeng, Shelya X., Lu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371866/
https://www.ncbi.nlm.nih.gov/pubmed/32686661
http://dx.doi.org/10.1038/s41419-020-02758-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371866/
https://www.ncbi.nlm.nih.gov/pubmed/32686661
http://dx.doi.org/10.1038/s41419-020-02758-6

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