Increasing endogenous activity of NMDARs on GABAergic neurons increases inhibition, alters sensory processing and prevents noise-induced tinnitus

Selective enhancement of GABAergic inhibition is thought to impact many vital brain functions and interferes with the genesis and/or progression of numerous brain disorders. Here, we show that selectively increasing NMDA receptor activity in inhibitory neurons using an NMDAR positive allosteric modu...

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Detalles Bibliográficos
Autores principales: Deng, Di, Masri, Samer, Yao, Lulu, Ma, Xiaoyan, Cao, Xuebing, Yang, Sungchil, Bao, Shaowen, Zhou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371882/
https://www.ncbi.nlm.nih.gov/pubmed/32686710
http://dx.doi.org/10.1038/s41598-020-68652-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371882/
https://www.ncbi.nlm.nih.gov/pubmed/32686710
http://dx.doi.org/10.1038/s41598-020-68652-5

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