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Increasing endogenous activity of NMDARs on GABAergic neurons increases inhibition, alters sensory processing and prevents noise-induced tinnitus
Selective enhancement of GABAergic inhibition is thought to impact many vital brain functions and interferes with the genesis and/or progression of numerous brain disorders. Here, we show that selectively increasing NMDA receptor activity in inhibitory neurons using an NMDAR positive allosteric modu...
Autores principales: | Deng, Di, Masri, Samer, Yao, Lulu, Ma, Xiaoyan, Cao, Xuebing, Yang, Sungchil, Bao, Shaowen, Zhou, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371882/ https://www.ncbi.nlm.nih.gov/pubmed/32686710 http://dx.doi.org/10.1038/s41598-020-68652-5 |
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