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Interleukin-22 deficiency alleviates doxorubicin-induced oxidative stress and cardiac injury via the p38 MAPK/macrophage/Fizz3 axis in mice

Several interleukin (IL) family members have been demonstrated to be involved in doxorubicin (DOX)-induced cardiac injury. This study aimed to investigate the role of IL-22 in DOX-induced cardiac injury and explore its possible mechanisms. In this study, mice were given DOX, and the cardiac expressi...

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Detalles Bibliográficos
Autores principales: Ye, Jing, Wang, Yuan, Xu, Yao, Wang, Zhen, Liu, Ling, Wang, Menglong, Ye, Di, Zhang, Jishou, Yang, Zicong, Lin, Yingzhong, Ji, Qingwei, Wan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371904/
https://www.ncbi.nlm.nih.gov/pubmed/32863209
http://dx.doi.org/10.1016/j.redox.2020.101636