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Metabolic reprogramming sustains cancer cell survival following extracellular matrix detachment
Epithelial cells require attachment to a support, such as the extracellular matrix, for survival. During cancer progression and metastasis, cancerous epithelial cells must overcome their dependence on adhesion signals. Dependence on glucose metabolism is a hallmark of cancer cells, but the nutrient...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371916/ https://www.ncbi.nlm.nih.gov/pubmed/32863227 http://dx.doi.org/10.1016/j.redox.2020.101643 |