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Role of Epigenetic Modifications in Inhibitory Immune Checkpoints in Cancer Development and Progression

A balance between co-inhibitory and co-stimulatory signals in the tumor microenvironment (TME) is critical to suppress tumor development and progression, primarily via maintaining effective immunosurveillance. Aberrant expression of immune checkpoints (ICs), including programmed cell death protein 1...

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Detalles Bibliográficos
Autores principales: Saleh, Reem, Toor, Salman M., Sasidharan Nair, Varun, Elkord, Eyad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371937/
https://www.ncbi.nlm.nih.gov/pubmed/32760400
http://dx.doi.org/10.3389/fimmu.2020.01469