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Verbascoside Protects Mice From Clostridial Gas Gangrene by Inhibiting the Activity of Alpha Toxin and Perfringolysin O

Gas gangrene, caused mainly by the anaerobic bacterium Clostridium perfringens (C. perfringens), causes death within 48 h of onset. Limited therapeutic strategies are available, and it is associated with extremely high mortality. Both C. perfringens alpha toxin (CPA) and perfringolysin O (PFO) are i...

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Detalles Bibliográficos
Autores principales: Zhang, Jian, Liu, Shui, Xia, Lining, Wen, Zhongmei, Hu, Naiyu, Wang, Tingting, Deng, Xuming, He, Jiakang, Wang, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371946/
https://www.ncbi.nlm.nih.gov/pubmed/32760362
http://dx.doi.org/10.3389/fmicb.2020.01504