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Alox12/15 Deficiency Exacerbates, While Lipoxin A(4) Ameliorates Hepatic Inflammation in Murine Alcoholic Hepatitis

Alcoholism is one of the leading and increasingly prevalent reasons of liver associated morbidity and mortality worldwide. Alcoholic hepatitis (AH) constitutes a severe disease with currently no satisfying treatment options. Lipoxin A(4) (LXA(4)), a 15-lipoxygenase (ALOX15)-dependent lipid mediator...

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Detalles Bibliográficos
Autores principales: Queck, Alexander, Fink, Annika F., Sirait-Fischer, Evelyn, Rüschenbaum, Sabrina, Thomas, Dominique, Snodgrass, Ryan G., Geisslinger, Gerd, Baba, Hideo A., Trebicka, Jonel, Zeuzem, Stefan, Weigert, Andreas, Lange, Christian M., Brüne, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371948/
https://www.ncbi.nlm.nih.gov/pubmed/32760397
http://dx.doi.org/10.3389/fimmu.2020.01447