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Alox12/15 Deficiency Exacerbates, While Lipoxin A(4) Ameliorates Hepatic Inflammation in Murine Alcoholic Hepatitis
Alcoholism is one of the leading and increasingly prevalent reasons of liver associated morbidity and mortality worldwide. Alcoholic hepatitis (AH) constitutes a severe disease with currently no satisfying treatment options. Lipoxin A(4) (LXA(4)), a 15-lipoxygenase (ALOX15)-dependent lipid mediator...
Autores principales: | Queck, Alexander, Fink, Annika F., Sirait-Fischer, Evelyn, Rüschenbaum, Sabrina, Thomas, Dominique, Snodgrass, Ryan G., Geisslinger, Gerd, Baba, Hideo A., Trebicka, Jonel, Zeuzem, Stefan, Weigert, Andreas, Lange, Christian M., Brüne, Bernhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371948/ https://www.ncbi.nlm.nih.gov/pubmed/32760397 http://dx.doi.org/10.3389/fimmu.2020.01447 |
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