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Heparan Sulfate Proteoglycan Clustering in Wnt Signaling and Dispersal
Wnt, a family of secreted signal proteins, serves diverse functions in animal development, stem cell systems, and carcinogenesis. Although Wnt is generally considered a morphogen, the mechanism by which Wnt ligands disperse is still debated. Heparan sulfate proteoglycans (HSPGs) are extracellular re...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371957/ https://www.ncbi.nlm.nih.gov/pubmed/32760727 http://dx.doi.org/10.3389/fcell.2020.00631 |