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Heparan Sulfate Proteoglycan Clustering in Wnt Signaling and Dispersal

Wnt, a family of secreted signal proteins, serves diverse functions in animal development, stem cell systems, and carcinogenesis. Although Wnt is generally considered a morphogen, the mechanism by which Wnt ligands disperse is still debated. Heparan sulfate proteoglycans (HSPGs) are extracellular re...

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Detalles Bibliográficos
Autores principales: Mii, Yusuke, Takada, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371957/
https://www.ncbi.nlm.nih.gov/pubmed/32760727
http://dx.doi.org/10.3389/fcell.2020.00631