A novel compound DBZ ameliorates neuroinflammation in LPS-stimulated microglia and ischemic stroke rats: Role of Akt(Ser473)/GSK3β(Ser9)-mediated Nrf2 activation

Microglia-mediated neuroinflammation plays a crucial role in the pathophysiological process of multiple neurological disorders such as ischemic stroke, yet lacks effective therapeutic agents. Previously, we discovered one novel synthetic compound, tanshinol borneol ester (DBZ), possesses anti-inflam...

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Detalles Bibliográficos
Autores principales: Liao, Sha, Wu, Jingni, Liu, Ruimin, Wang, Shixiang, Luo, Jing, Yang, Yang, Qin, Yannan, Li, Tao, Zheng, Xiaopu, Song, Jing, Zhao, Xinfeng, Xiao, Chaoni, Zhang, Yajun, Bian, Liujiao, Jia, Pu, Bai, Yajun, Zheng, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371982/
https://www.ncbi.nlm.nih.gov/pubmed/32863210
http://dx.doi.org/10.1016/j.redox.2020.101644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371982/
https://www.ncbi.nlm.nih.gov/pubmed/32863210
http://dx.doi.org/10.1016/j.redox.2020.101644

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