Ectodermal Organ Development Is Regulated by a microRNA-26b-Lef-1-Wnt Signaling Axis

The developmental role of Lef-1 in ectodermal organs has been characterized using Lef-1 murine knockout models. We generated a Lef-1 conditional over-expression (COEL) mouse to determine the role of Lef-1 expression in epithelial structures at later stages of development after endogenous expression...

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Detalles Bibliográficos
Autores principales: Eliason, Steve, Sharp, Thad, Sweat, Mason, Sweat, Yan Y., Amendt, Brad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372039/
https://www.ncbi.nlm.nih.gov/pubmed/32760291
http://dx.doi.org/10.3389/fphys.2020.00780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372039/
https://www.ncbi.nlm.nih.gov/pubmed/32760291
http://dx.doi.org/10.3389/fphys.2020.00780

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