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Ectodermal Organ Development Is Regulated by a microRNA-26b-Lef-1-Wnt Signaling Axis
The developmental role of Lef-1 in ectodermal organs has been characterized using Lef-1 murine knockout models. We generated a Lef-1 conditional over-expression (COEL) mouse to determine the role of Lef-1 expression in epithelial structures at later stages of development after endogenous expression...
Autores principales: | Eliason, Steve, Sharp, Thad, Sweat, Mason, Sweat, Yan Y., Amendt, Brad A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372039/ https://www.ncbi.nlm.nih.gov/pubmed/32760291 http://dx.doi.org/10.3389/fphys.2020.00780 |
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