Differences in HBV Replication, APOBEC3 Family Expression, and Inflammatory Cytokine Levels Between Wild-Type HBV and Pre-core (G1896A) or Basal Core Promoter (A1762T/G1764A) Mutants

BACKGROUND: Chronic hepatitis B virus (HBV) infection is the leading cause of hepatocellular carcinoma (HCC) world-wide. HBV variants, particularly the G1896A pre-core (PC) and A1762T/G1764A basal core promoter (BCP) mutations, are established risk factors for cirrhosis and HCC, but the molecular bi...

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Detalles Bibliográficos
Autores principales: Lau, Keith C. K., Joshi, Shivali S., Mahoney, Douglas J., Mason, Andrew L., van Marle, Guido, Osiowy, Carla, Coffin, Carla S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372132/
https://www.ncbi.nlm.nih.gov/pubmed/32760388
http://dx.doi.org/10.3389/fmicb.2020.01653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372132/
https://www.ncbi.nlm.nih.gov/pubmed/32760388
http://dx.doi.org/10.3389/fmicb.2020.01653

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