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Targeting the Heme Oxygenase 1/Carbon Monoxide Pathway to Resolve Lung Hyper-Inflammation and Restore a Regulated Immune Response in Cystic Fibrosis

In individuals with cystic fibrosis (CF), lung hyper-inflammation starts early in life and is perpetuated by mucus obstruction and persistent bacterial infections. The continuous tissue damage and scarring caused by non-resolving inflammation leads to bronchiectasis and, ultimately, respiratory fail...

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Detalles Bibliográficos
Autores principales: Di Pietro, Caterina, Öz, Hasan H., Murray, Thomas S., Bruscia, Emanuela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372134/
https://www.ncbi.nlm.nih.gov/pubmed/32760278
http://dx.doi.org/10.3389/fphar.2020.01059